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recombinant human egf stimulation  (PeproTech)


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    Structured Review

    PeproTech recombinant human egf stimulation
    Recombinant Human Egf Stimulation, supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+egf+stimulation/pmc03868753-69-0-7?v=PeproTech
    Average 90 stars, based on 1 article reviews
    recombinant human egf stimulation - by Bioz Stars, 2026-08
    90/100 stars

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    R&D Systems stimulation
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    Image Search Results


    Testing GSA predictions of drug targets in ErbB2/3 network. Experimental confirmation of drug targets, predicted by GSA, in PE04 (A and B) and OVCAR4 (C and D) cell lines: time course profile (left) and integrated pAkt response (right) to heregulin-β stimulation ± pertuzumab (Per), LY294002 (LY) and UCN-01 (UCN). All integrals were normalised on the value of S pAkt observed in the absence of any inhibitors. The error-bars indicate 95% confidence intervals of technical replicates.

    Journal: European Journal of Pharmaceutical Sciences

    Article Title: Model-based global sensitivity analysis as applied to identification of anti-cancer drug targets and biomarkers of drug resistance in the ErbB2/3 network

    doi: 10.1016/j.ejps.2011.10.026

    Figure Lengend Snippet: Testing GSA predictions of drug targets in ErbB2/3 network. Experimental confirmation of drug targets, predicted by GSA, in PE04 (A and B) and OVCAR4 (C and D) cell lines: time course profile (left) and integrated pAkt response (right) to heregulin-β stimulation ± pertuzumab (Per), LY294002 (LY) and UCN-01 (UCN). All integrals were normalised on the value of S pAkt observed in the absence of any inhibitors. The error-bars indicate 95% confidence intervals of technical replicates.

    Article Snippet: Cells were treated with UCN-01 (protein kinase inhibitor; Calbiochem #539644; final concentration of 1 μM), LY294002 (PI3 kinase inhibitor; Calbiochem #440204; final concentration 20 μM), Pertuzumab (ErbB2 inhibitor; final concentration 100 nM) and stimulation by Heregulin (R&D Systems; 396-HB-CF) was at final concentration of 1 nM.

    Techniques:

    Experimental testing of GSA-derived combination therapies. Integrated pAkt response to heregulin-β stimulation in PE04 (left) and OVCAR4 (right) cell lines, treated with combinations of pertuzumab, LY294002 (LY) and UCN-01 (UCN). The data were normalised on the AUC of pAkt time-course in the absence of any drugs.

    Journal: European Journal of Pharmaceutical Sciences

    Article Title: Model-based global sensitivity analysis as applied to identification of anti-cancer drug targets and biomarkers of drug resistance in the ErbB2/3 network

    doi: 10.1016/j.ejps.2011.10.026

    Figure Lengend Snippet: Experimental testing of GSA-derived combination therapies. Integrated pAkt response to heregulin-β stimulation in PE04 (left) and OVCAR4 (right) cell lines, treated with combinations of pertuzumab, LY294002 (LY) and UCN-01 (UCN). The data were normalised on the AUC of pAkt time-course in the absence of any drugs.

    Article Snippet: Cells were treated with UCN-01 (protein kinase inhibitor; Calbiochem #539644; final concentration of 1 μM), LY294002 (PI3 kinase inhibitor; Calbiochem #440204; final concentration 20 μM), Pertuzumab (ErbB2 inhibitor; final concentration 100 nM) and stimulation by Heregulin (R&D Systems; 396-HB-CF) was at final concentration of 1 nM.

    Techniques: Derivative Assay